Related Experiment Video
Updated: May 4, 2026
Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
The obsessive compulsive spectrum in schizophrenia, a meta-analysis and meta-regression exploring prevalence rates
Marije Swets1, Jack Dekker2, Katelijne van Emmerik-van Oortmerssen3
1Arkin Mental Health and Addiction Treatment Centre, Amsterdam, The Netherlands.
Aims:
The aims of this study were to conduct a meta-analysis and meta-regression to estimate the prevalence rates for obsessive compulsive symptoms (OCS) and obsessive compulsive disorder (OCD) in schizophrenia, and to investigate what influences these prevalence rates.
Method:
Studies were identified via an online OVID database search, including PsychInfo, Embase and Medline until December 2009.
Results:
Forty-three studies summarizing outcomes for 3978 subjects met inclusion criteria. The mean OCD prevalence is 12.3%, slightly increasing to 13.6% after adjustment in meta-regression. The prevalence rate of OCS, defined as any obsession or compulsion is 30.7% (30.3% adjusted). Higher severity of OCS, DIGS assessment, and Sub-Saharan African origin of study are associated with a lower OCS/OCD prevalence rate, use of DSM-IV edition, Y-BOCS assessment and longer schizophrenia history are associated with a higher prevalence rate.
Conclusion:
The prevalence of OCS and OCD in schizophrenia is substantial, specifically in more chronic patient populations and is influenced by the method of assessment.
More Related Videos
09:14Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
06:26Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI
Published on: November 27, 2019
Related Concept Videos
01:28Obsessive-Compulsive Disorder
01:29Psychological and Sociocultural Causes of Schizophrenia
01:24Personality Disorders: Dependent and Obsessive-Compulsive
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle...
01:29Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
01:27Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
01:17Schizophrenia