Delivering pediatric HIV care in resource-limited settings: cost considerations in an expanded response

Michael A Tolle1, B Ryan Phelps, Chris Desmond

  • 1aBaylor College of Medicine Children's Foundation - Tanzania, Bugando Medical Centre, Mwanza, Tanzania bUnited States Agency for International Development, Washington, DC, USA cDevelopment Pathways to Health Research Unit, University of Witwatersrand, Johannesburg dClinton Health Access Initiative eUnited Nations Children's Fund (UNICEF), New York, New York fPartnership for Supply Chain Management, Arlington, Virginia, USA gBaylor College of Medicine Children's Foundation-Malawi, Kamuzu Central Hospital, Lilongwe, Malawi hWorld Health Organization, Geneva, Switzerland iManagement Sciences for Health, Cambridge, Massachusetts, USA.

AIDS (London, England)
|December 24, 2013
PubMed

Insights

Expanding pediatric HIV treatment is crucial alongside prevention of mother-to-child transmission (PMTCT) programs. Prioritizing efficient interventions for HIV-infected children ensures better resource allocation and saves lives.

Area of Science:

  • Public Health
  • Pediatric Infectious Diseases
  • Health Economics

Background:

  • Protection of children from HIV requires integrating prevention of mother-to-child transmission (PMTCT) with expanded pediatric treatment.
  • Treating HIV-infected children is ethically imperative, despite high costs, due to humanitarian, equity, and children's rights considerations.
  • Inefficiencies in resource allocation within limited budgets can lead to reduced service coverage and effectiveness, impacting children's lives.

Purpose of the Study:

  • To review cost drivers in pediatric HIV interventions.
  • To identify strategies for enhancing efficiency in pediatric HIV programming.
  • To inform the design and scale-up of cost-effective pediatric HIV treatment programs.

Main Methods:

  • Literature review of existing knowledge on cost drivers in pediatric HIV interventions.
  • Analysis of high-impact interventions with disproportional returns on investment.
  • Formulation of recommendations for improving efficiency in pediatric HIV programming.

Main Results:

  • Identification of key cost drivers influencing the provision of pediatric HIV treatment.
  • Highlighting of specific high-impact interventions that offer significant returns on investment.
  • Development of strategies to optimize resource utilization for treating HIV-infected children.

Conclusions:

  • Efficient pediatric HIV treatment programs are essential for maximizing the impact of available resources.
  • Prioritizing and scaling up high-impact interventions can improve outcomes for HIV-infected children.
  • Sustained progress towards universal access requires increased funding and better data on intervention costs and outcomes.

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
408
Methods Of Healthcare Delivery System01:26

Methods Of Healthcare Delivery System

At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.9K
Specialized Care Centers and Settings-II01:30

Specialized Care Centers and Settings-II

Rural Health Centers
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
1.1K
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
43.0K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
1.0K
International Nursing Organizations II01:28

International Nursing Organizations II

The World Health Organization (WHO) is a specialized agency of the United Nations based in Geneva. The WHO has many initiatives that center around health. Primarily, they lead global efforts to expand universal health coverage using science-based policies and programs. They are also responsible for shaping health research agendas and developing norms and standards.
The WHO provides expert team support, including funding, vaccines, testing, and treatment tools at the country level to fight...
1.4K