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Related Experiment Videos

Chronotropic response of an activity detecting pacemaker compared with the normal sinus node.

P J Moura, L J Gessman, T Lai

    Pacing and Clinical Electrophysiology : PACE
    |January 1, 1987
    PubMed
    Summary
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    The Medtronic Activitrax pacemaker effectively mimics normal heart rate responses to physical activity. Programmed appropriately, it provides physiologic pacing, adapting to daily activities similar to the natural sinus node.

    Area of Science:

    • Cardiology
    • Biomedical Engineering
    • Medical Devices

    Background:

    • Single chamber pacemakers require rate responsiveness to mimic normal sinus node function during activity.
    • The Medtronic Activitrax is an activity-detecting pacemaker designed to adjust pacing rate based on physical exertion.

    Purpose of the Study:

    • To compare the rate responsiveness of the Medtronic Activitrax pacemaker to the normal sinus node.
    • To evaluate the device's ability to simulate natural heart rate acceleration and deceleration during physical activity.

    Main Methods:

    • The study involved six healthy volunteers and 12 patients implanted with the Activitrax pacemaker.
    • Participants underwent exercise testing with the pacemaker in Activity mode, programmed at various thresholds and response settings.

    Related Experiment Videos

  • Pacing rates were compared to normal sinus node rates during activities like arm waving, jumping, and walking.

    • Main Results:

    • At high activity threshold and response settings, no significant difference was observed between pacemaker and sinus node rates during stress tests.
    • A significant difference was noted at a medium activity threshold during submaximal stress testing (141 bpm sinus vs. 105 bpm pacing).
    • The Activitrax successfully simulated typical sinus node rate changes in patients during exercise, regardless of implantation site.

    Conclusions:

    • The Medtronic Activitrax pacemaker demonstrates comparable rate responsiveness to the normal sinus node during various physical activities.
    • Appropriate programming allows the Activitrax to achieve physiologic pacing rates, effectively responding to daily activities.
    • The device functions normally post-implantation, offering a viable option for activity-responsive pacing.