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Related Experiment Videos

The Swedish experience in phrenic nerve stimulation.

H Fodstad

    Pacing and Clinical Electrophysiology : PACE
    |January 1, 1987
    PubMed
    Summary

    Phrenic nerve stimulators improved breathing for some patients with central respiratory insufficiency and chronic hiccups. Diaphragm pacing offered significant independence from ventilators in a majority of eligible patients.

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    Area of Science:

    • Neurology
    • Pulmonology
    • Biomedical Engineering

    Background:

    • Respiratory insufficiency of central nervous origin presents significant challenges.
    • Chronic singultus (hiccups) can be debilitating and difficult to manage.
    • Conventional respiratory support has limitations for certain patient populations.

    Purpose of the Study:

    • To evaluate the efficacy of phrenic nerve stimulators (diaphragm pacers) in patients with central respiratory insufficiency.
    • To assess the impact of diaphragm pacing on ventilator dependence.
    • To determine the effectiveness of phrenic nerve stimulation for chronic singultus.

    Main Methods:

    • Implantation of phrenic nerve stimulators in 20 patients.
    • Follow-up period ranging from 2 to 84 months (mean 41 months).
    • Assessment of respiratory independence and management of chronic singultus.

    Main Results:

    • Ten patients achieved complete independence from conventional respirators.
    • Two patients became partially dependent on respirators.
    • Five patients experienced limited or no benefit from diaphragm pacing, including two with hiccups.

    Conclusions:

    • Diaphragm pacing is a viable treatment option for select patients with central respiratory insufficiency, offering significant ventilator independence.
    • Phrenic nerve stimulation shows potential in managing chronic singultus, though results vary.
    • Further research is warranted to optimize patient selection and pacing parameters for improved outcomes.

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