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A highly sensitive ratiometric fluorescent probe with a large emission shift for imaging endogenous cysteine in
Baocun Zhu1, Bingpeng Guo1, Yunzhou Zhao1
1School of Resources and Environment, University of Jinan, Shandong Provincial Engineering Technology Research Center for Ecological Carbon Sink and Capture Utilization, Jinan 250022, China.
Abstract:
A new design strategy for the construction of ratiometric fluorescent probe with a large emission shift was developed. Based on this strategy, a highly selective and sensitive colorimetric and ratiometic fluorescent probe for cysteine (Cys) with a 117 nm red-shifted emission was synthesized and applied to the ratiometric imaging of endogenous Cys in living cells.

