Histopathological study of endoscopic biopsies
Rupendra Thapa1, Mamta Lakhey1, Pradeep Kumar Yadav2
1Department of Pathology, Kathmandu Medical College, Sinamangal, Kathmandu, Medicare National Hospital and Research Centre, Chabahil, Kathmandu, Nepal.
JNMA; Journal of the Nepal Medical Association
|December 24, 2013
Summary
Histopathological analysis of endoscopic gastric biopsies revealed that non-neoplastic lesions, particularly mild chronic gastritis, were most common. Adenocarcinoma was the most frequent neoplastic finding in these upper gastrointestinal tract disease diagnoses.
Area of Science:
- Gastroenterology
- Pathology
- Oncology
Background:
- Upper gastrointestinal tract diseases contribute significantly to morbidity and mortality.
- Histopathological examination of endoscopic biopsies is crucial for accurate diagnosis and management.
- Understanding the spectrum of lesions is vital for patient care.
Purpose of the Study:
- To determine the histopathological patterns observed in endoscopic gastric biopsies.
- To identify the prevalence of neoplastic and non-neoplastic lesions.
- To establish the most common findings in gastric biopsies.
Main Methods:
- A descriptive study design was employed.
- Consecutive endoscopic gastric biopsies from patients of all ages and both sexes were analyzed over one year.
- Standard histopathological techniques were utilized for examination.
Main Results:
- The study included patients aged 20 to 84 years.
- Non-neoplastic lesions were found in 67.5% of cases, while neoplastic lesions were present in 32.5%.
- Mild chronic gastritis (27.5%) was the most common non-neoplastic lesion; adenocarcinoma was the most common neoplastic lesion.
Conclusions:
- Mild chronic gastritis is the predominant non-neoplastic finding in endoscopic gastric biopsies.
- Adenocarcinoma represents the most frequent neoplastic lesion encountered.
- Histopathological analysis of gastric biopsies is essential for diagnosing diverse upper GI pathologies.
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