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Amitraz poisoning treatment: still supportive?
Nastaran Eizadi-Mood1, Ali Mohammad Sabzghabaee2, Farzad Gheshlaghi1
1Department of Poisoning Emergencies, Noor General Teaching Hospital, Isfahan University of Medical Sciences.
Iranian Journal of Pharmaceutical Research : IJPR
|December 24, 2013
Summary
This case report details a successful supportive management of amitraz poisoning, a rare event. Early intervention with gastric lavage and activated charcoal aided recovery in a human intoxication case.
Area of Science:
- Toxicology
- Emergency Medicine
Background:
- Amitraz, an amidine and α2 adrenergic agonist, has limited reported human intoxication cases.
- A clear therapeutic protocol for amitraz poisoning is lacking, highlighting the value of case reports.
Purpose of the Study:
- To present a successfully managed case of human amitraz intoxication.
- To contribute to the clinical understanding and management of amitraz poisoning.
Main Methods:
- A 22-year-old female ingested 100 mL of 20% amitraz solution.
- Initial management included gastric lavage and activated charcoal.
- Subsequent supportive and symptomatic treatment was administered at a Poisoning Emergency Department.
Main Results:
- The patient presented with nausea, vomiting, dizziness, and miosis.
- Supportive care led to a successful recovery.
- Atropine is suggested for managing bradycardia and miosis in amitraz poisoning.
Conclusions:
- Amitraz poisoning can cause central nervous system depression and cardiovascular symptoms.
- Supportive and symptomatic management is key in treating amitraz intoxication.
- Further research on activated charcoal and cathartics in amitraz poisoning is warranted.
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