Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

657
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
657
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

3.3K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
3.3K
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

924
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
924
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

1.5K
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
1.5K
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

682
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
682
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

429
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
429

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predictors of Mortality in Children Admitted With Pneumonia to a Tertiary Hospital in Ghana: A Retrospective Cohort Study.

Health science reports·2026
Same author

Understanding system-level barriers to pediatric neuro-oncology in Ghana: Qualitative insights from frontline healthcare professionals.

Neuro-oncology advances·2026
Same author

Impact of introducing RTS,S/AS01<sub>E</sub> malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme.

Lancet (London, England)·2026
Same author

Family planning in the Atwima Nwabiagya North District: A follow-up on attitudes and practices.

Journal of public health in Africa·2026
Same author

Etiology of gene expression-based subtypes of breast cancer in the Ghana Breast Health Study.

International journal of cancer·2026
Same author

Breast Cancer Incidence Rates in Ghanaian and US Black Women From 2013 Through 2015.

JAMA network open·2025

Related Experiment Video

Updated: May 4, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.4K

Sickle cell disease: management options and challenges in developing countries.

Daniel Ansong1, Alex Osei Akoto1, Delaena Ocloo2

  • 1School of Medical Sciences,-Kwame Nkrumah University of Science and Technology, Kumasi-Ghana ; Department of Child Health, Komfo Anokye Teaching Hospital, Kumasi-Ghana.

Mediterranean Journal of Hematology and Infectious Diseases
|December 24, 2013
PubMed
Summary
This summary is machine-generated.

Sickle Cell Disease (SCD) management in developing nations faces resource challenges. Affordable interventions like early counseling, newborn screening, and vaccinations are crucial for improving patient care.

More Related Videos

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

18.8K
Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
08:23

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Published on: November 5, 2019

11.2K

Related Experiment Videos

Last Updated: May 4, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.4K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

18.8K
Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
08:23

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Published on: November 5, 2019

11.2K

Area of Science:

  • Hematology
  • Public Health
  • Global Health

Background:

  • Sickle Cell Disease (SCD) is a prevalent genetic hemoglobin disorder in sub-Saharan Africa.
  • Developing countries, such as Ghana, are initiating national newborn screening for SCD.
  • Significant morbidities include vaso-occlusive episodes, infections, Acute Chest Syndrome (ACS), stroke, and hip necrosis.

Purpose of the Study:

  • To examine SCD management options in developing countries.
  • To highlight challenges faced by healthcare professionals in resource-limited settings.
  • To propose effective and affordable interventions for SCD care.

Main Methods:

  • This commentary reviews current management strategies for SCD and its complications.
  • It analyzes the impact of resource limitations on clinical practice in developing countries.
  • It emphasizes preventive measures and healthcare worker training.

Main Results:

  • Management of SCD morbidities is less advanced in developing countries compared to developed nations.
  • Resource limitations significantly influence available management options.
  • Understanding disease progression and implementing preventive strategies are key.

Conclusions:

  • Clinicians in developing countries face substantial challenges in managing SCD.
  • Early counseling, newborn screening, antimicrobial prophylaxis, and vaccinations are vital.
  • Training healthcare workers, patients, and caregivers enhances SCD management affordability and effectiveness.