Related Experiment Video
Updated: May 4, 2026
08:31
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
3.7K
Transapical mitral valve implantation: the Lutter valve.
G Lutter1, S Pokorny1, D Frank2
1Department of Cardiovascular Surgery, Christian-Albrechts-University of Kiel, School of Medicine, Kiel, Germany.
Heart, Lung and Vessels
|December 24, 2013
Summary
Researchers developed a novel self-expanding nitinol valved stent for transcatheter mitral valve repair. This off-pump device offers a promising alternative for severe mitral regurgitation, especially in high-risk patients.
Area of Science:
- Cardiovascular Medicine
- Biomedical Engineering
- Medical Devices
Background:
- Severe mitral regurgitation necessitates advanced treatment options.
- Transcatheter techniques offer less invasive alternatives to open-heart surgery.
- Current challenges include secure device fixation in the mitral valve annulus.
Purpose of the Study:
- To review the development of a self-expanding nitinol valved stent for transapical implantation.
- To highlight design iterations aimed at improving stent performance and reducing complications.
- To present advances in creating a novel device for mitral valve treatment.
Main Methods:
- Iterative design and development of a self-expanding nitinol valved stent.
- Focus on achieving secure fixation, reducing paravalvular leakages, and enhancing reproducibility.
- Evaluation of stent performance in the beating heart context.
Main Results:
- A prototype valved stent was developed through multiple design iterations.
- The prototype demonstrated secure deployment and high reproducibility.
- Low rates of paravalvular leakage and mild stent deformation were observed.
Conclusions:
- The developed nitinol valved stent shows potential for treating severe mitral regurgitation.
- Further long-term in vivo trials are required before clinical application.
- This transcatheter approach offers a promising alternative for high-risk patients.
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