Neurologic complications of congenital heart disease and its treatment
Related Experiment Video
Updated: May 4, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Emily de Los Reyes1, E Steve Roach1
1Division of Child Neurology, Ohio State University, Columbus, OH, USA.
Insights
Congenital heart disease can lead to neurologic complications like stroke, especially with severe defects. Surgical correction may also cause neurological issues, requiring careful management.
Area of Science:
- Cardiology
- Neurology
- Pediatrics
Background:
- Improved survival rates for congenital cardiac anomalies are noted.
- Neurologic complications, including cognitive impairment and stroke, are recognized in this population.
- Severe structural defects increase stroke risk.
Purpose of the Study:
- To review neurologic complications associated with congenital heart disease.
- To identify risk factors for stroke in patients with congenital heart defects.
- To discuss complications arising from cardiac anomaly correction.
Main Methods:
- Literature review of neurologic complications in congenital heart disease.
- Analysis of stroke risk factors in various congenital heart defects.
- Examination of neurological sequelae post-cardiac surgery.
Main Results:
- Severe defects like tetralogy of Fallot, transposition of great arteries, and hypoplastic left heart syndrome carry the highest stroke risk.
- Persistent foramen ovale poses minimal additional stroke risk unless co-occurring with other anomalies.
- Genetic causes of congenital heart disease often present with additional anomalies.
- Seizures, ischemia, stroke, and movement disorders are complications post-cardiac correction.
Conclusions:
- Neurologic complications are significant in individuals with congenital heart disease.
- Risk stratification for stroke is crucial, particularly in severe cardiac defects.
- Comprehensive management should address both cardiac and potential neurologic sequelae.
Abstract:
Advances in surgical and medical management have dramatically improved the survival of individuals with congenital cardiac anomalies. Various neurologic complications occur in association with congenital heart disease, including cognitive impairment and ischemic stroke. The likelihood of stroke is greatest in individuals with severe structural cardiac defects such as tetralogy of Fallot, transposition of the great arteries, or hypoplastic left heart syndrome. A persistent foramen ovale adds little or no additional stroke risk unless it is associated with an atrial septal aneurysm or other anomaly. Individuals with congenital heart disease caused by genetic abnormalities are apt to have other anomalies as well. Complications related to correction of cardiac anomalies include seizures, ischemia, stroke, and movement disorders.
Related Concept Videos
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Mitral Stenosis IV: Nursing Management
Heart Failure V: Medical Management

