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Nervous system disorders in dialysis patients
Vinod K Bansal1, Seema Bansal2
1Division of Nephrology and Hypertension, Loyola University Medical Center, Maywood, IL, USA.
Handbook of Clinical Neurology
|December 25, 2013
Summary
Dialysis patients frequently experience neurologic complications impacting well-being. This review covers central and peripheral nervous system disorders, including encephalopathy, neuropathies, and sleep disturbances, offering therapeutic insights.
Area of Science:
- Nephrology
- Neurology
Background:
- Neurologic complications are common in dialysis patients, stemming from uremia or the dialysis process itself.
- These complications significantly impact patient morbidity, mortality, and quality of life, especially with increased patient survival.
- Central nervous system issues like uremic encephalopathy and dialysis disequilibrium syndrome are less common due to better understanding and treatment.
Purpose of the Study:
- To review the clinical and pathophysiologic aspects of nervous system disorders in patients undergoing dialysis.
- To discuss current therapeutic strategies for managing neurologic complications in this population.
Main Methods:
- Literature review and synthesis of existing knowledge on neurologic complications in dialysis patients.
- Discussion of central and peripheral nervous system manifestations.
Main Results:
- Common neurologic issues include atherosclerosis, stroke, and neuropathies, which are not significantly altered by dialysis.
- Increasing recognition of sleep disorders in dialysis patients.
- Peripheral nervous system involvement, such as myopathy, is also observed.
Conclusions:
- Nervous system disorders are a significant concern for dialysis patients, affecting their overall health.
- Comprehensive assessment and therapeutic interventions are crucial for managing these complications.
- Further research into the pathogenesis and treatment of these neurologic issues is warranted.
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