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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Related Experiment Video

Updated: May 4, 2026

Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity AIDN: A Translational Neuroscience Approach
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Neurodermatology.

Jean-Philippe Neau1, Gaëlle Godeneche1, Stéphane Mathis1

  • 1Department of Neurology, CHU La Milétrie, Poitiers, France.

Handbook of Clinical Neurology
|December 25, 2013
PubMed
Summary
This summary is machine-generated.

Skin and nervous system diseases often co-occur due to their shared origin. Recognizing cutaneous manifestations aids in diagnosing neurologic conditions and guiding treatment.

Keywords:
Dermatological symptomsbrain and peripheral tumorscognitive deficitcutaneous angiomaepilepsygenetic disordersperipheral neuropathystroke

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Area of Science:

  • Neurocutaneous Medicine
  • Dermatology and Neurology

Background:

  • The skin and the central/peripheral nervous system originate from the ectoderm.
  • Genetic and acquired diseases can affect both systems simultaneously.

Purpose of the Study:

  • To highlight the link between neurologic disorders and cutaneous manifestations.
  • To emphasize the importance of dermatological examination in neurology.

Main Methods:

  • Review of conditions affecting both skin and nervous system.
  • Clinical observation and diagnostic correlation.

Main Results:

  • Specific skin, hair, and nail abnormalities can indicate underlying neurologic diseases.
  • Early identification of cutaneous signs can facilitate diagnosis of conditions like stroke, tumors, epilepsy, and cognitive disorders.

Conclusions:

  • Neurologists should carefully examine skin, hair, and nails for diagnostic clues.
  • Dermatologist consultation is recommended for complex or unusual skin findings in neurologic patients.