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A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
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Iatrogenic neurology.

Luciano A Sposato1, Osvaldo Fustinoni2

  • 1Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada.

Handbook of Clinical Neurology
|December 25, 2013
PubMed
Summary
This summary is machine-generated.

Iatrogenic neurologic diseases, often caused by medications, are a frequent cause of hospital admissions and a significant public health concern. These drug-induced conditions affecting the nervous system are frequently overlooked in neurological diagnoses.

Keywords:
Iatrogenic neurologydrug toxicitydrugs and brainneurologic toxicityneurological adverse effectsneurotoxic complicationsneurotoxic effectsneurotoxicitytoxic complications

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Area of Science:

  • Neurology
  • Clinical Pharmacology
  • Public Health

Background:

  • Iatrogenic diseases are a common cause of hospital admissions, representing a significant public health issue.
  • Pharmacologic causes are the most frequent type of iatrogenic neurologic disease, impacting both central and peripheral nervous systems.
  • These conditions are often overlooked in the differential diagnosis of neurologic patients.

Purpose of the Study:

  • To comprehensively review common and uncommon forms of drug toxicity causing iatrogenic neurologic disease.
  • To highlight the vulnerability of the central and peripheral nervous systems to pharmacologic agents.
  • To emphasize the importance of considering iatrogenic causes in neurologic patient evaluations.

Main Methods:

  • Comprehensive review of literature on drug-induced neurologic adverse effects.
  • Inclusion of tables listing a majority of neurologic adverse effects.
  • Detailed discussion of the most relevant and significant iatrogenic neurologic issues.

Main Results:

  • Pharmacologic agents are a primary cause of iatrogenic neurologic disease.
  • The clinical spectrum of these drug-induced conditions ranges from mild to fatal.
  • A wide array of drug toxicities impacting the nervous system are presented.

Conclusions:

  • Iatrogenic neurologic disease, particularly pharmacologic, is a critical and often underestimated diagnostic consideration.
  • Awareness and recognition of drug toxicity are essential for accurate neurologic diagnosis and patient management.
  • This review provides a comprehensive resource for understanding and addressing drug-induced neurologic conditions.