Related Experiment Video
Updated: May 4, 2026

Synthesis and Microdiffraction at Extreme Pressures and Temperatures
Published on: October 7, 2013
X-ray reflectivity measurements of liquid/solid interfaces under high hydrostatic pressure conditions
Florian J Wirkert1, Michael Paulus1, Julia Nase1
1Fakultät Physik/DELTA, TU Dortmund, 44221 Dortmund, Germany.
Abstract:
A high-pressure cell for in situ X-ray reflectivity measurements of liquid/solid interfaces at hydrostatic pressures up to 500 MPa (5 kbar), a pressure regime that is particularly important for the study of protein unfolding, is presented. The original set-up of this hydrostatic high-pressure cell is discussed and its unique properties are demonstrated by the investigation of pressure-induced adsorption of the protein lysozyme onto hydrophobic silicon wafers. The presented results emphasize the enormous potential of X-ray reflectivity studies under high hydrostatic pressure conditions for the in situ investigation of adsorption phenomena in biological systems.
More Related Videos
08:42High-Sensitivity Nuclear Magnetic Resonance at Giga-Pascal Pressures: A New Tool for Probing Electronic and Chemical Properties of Condensed Matter under Extreme Conditions
Published on: October 10, 2014
10:36Stress Distribution During Cold Compression of Rocks and Mineral Aggregates Using Synchrotron-based X-Ray Diffraction
Published on: May 20, 2018
Related Concept Videos
Measurement of Fluid Pressure
A basic form of manometer is the piezometer, a vertical tube open at the top and filled with the same...
Applications of Integration to Find Hydrostatic Pressure
Hydrostatic Pressure Force on a Curved Surface