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Statin use is not associated with reduced risk of skin cancer: a meta-analysis
1Department of Epidemiology, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, China.
Background:
There is contradictory evidence about the association between statin and skin cancer.
Methods:
Literature search in PubMed and Web of Science was undertaken up to June 2013. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated.
Result:
A total of 21 articles with 29 studies were identified. No association was found between statin and skin cancer among neither melanoma (RR, 0.94; 95% CI, 0.85-1.04) nor non-melanoma skin cancer (RR, 1.03; 95% CI, 0.90-1.19).
Conclusion:
Our meta-analysis does not support a potential role of statin use in the prevention of skin cancer.
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