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Published on: July 5, 2011
Review article: Venous thromboembolism after total joint replacement
1Department of Orthopaedics and Traumatology, Queen Mary Hospital, Hong Kong.
Abstract:
Venous thromboembolism can occur in up to 84% of cases following total joint replacement. It can result in pain, swelling, chronic post-thrombotic syndrome, and pulmonary embolism. Its prevention is vital to the success of the surgery. To achieve a safe and effective prophylaxis, a combination of mechanical and pharmacologic agents should be used. New generation of thromboprophylactic agents target different factors of the coagulation pathway.
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