Related Experiment Video
Updated: May 4, 2026

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
Published on: May 28, 2021
Haloarcula marismortui archaellin genes as ecoparalogs
Alexey S Syutkin1, Mikhail G Pyatibratov, Oxana V Galzitskaya
1Institute of Protein Research, Russian Academy of Sciences, 142290, Pushchino, Moscow Region, Russia, alexeysyutkin@gmail.com.
Abstract:
The genome of haloarchaeon Haloarcula marismortui contains two archaellin genes-flaA2 and flaB. Earlier we isolated and characterized two H. marismortui strains in that archaella consisting of FlaA2 archaellin (with a minor FlaB fraction) or of FlaB only. Both the FlaA2 and FlaB strains were motile and produced functional helical archaella. Thus, it may seem that the FlaA2 archaellin is redundant. In this study we investigated the biological roles of archaellin redundancy and demonstrated that FlaA2 archaellin is better adapted to more severe conditions of high temperature/low salinity, while FlaB has an advantage with increasing salinity. We used the thermodynamic data and bioinformatics sequence analysis to demonstrate that archaella formed by FlaA2 are more stable than those formed by FlaB. Our combined data indicate that the monomer FlaA2 archaellin is more flexible and leads to more compact and stable formation of filamentous structures. The difference in response to environmental stress indicates that FlaA2 and FlaB replace each other under different environmental conditions and can be considered as ecoparalogs.
More Related Videos
09:06Removal of Exogenous Materials from the Outer Portion of Frozen Cores to Investigate the Ancient Biological Communities Harbored Inside
Published on: July 3, 2016
10:55Ablation of a Single Cell From Eight-cell Embryos of the Amphipod Crustacean Parhyale hawaiensis
Published on: March 16, 2014
Related Concept Videos
Diversity of Archaea II
Surface Appendages of Archaea
Diversity of Archaea I
Diversity of Archaea III
Archaeal Cell Wall
Diversity of Protists I