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Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
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Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

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Pseudotumor of the Hip due to Fungal Prosthetic Joint Infection

Stefano Artiaco1, Andrea Ferrero2, Frediano Boggio1

  • 1Department of Orthopaedics and Traumatology, Orthopaedic and Trauma Center, Via Zuretti 29, 10126 Turin, Italy.

Case Reports in Orthopedics
|December 26, 2013
PubMed

Insights

This study details a rare case of Candida albicans causing a hip joint pseudotumor after total hip arthroplasty. Fungal infections can present as pseudotumors, especially in immunocompromised patients.

Area of Science:

  • Orthopedic Surgery
  • Infectious Diseases
  • Medical Mycology

Background:

  • Pseudotumors in total hip arthroplasty (THA) are typically linked to material wear (metal-on-metal, metal-on-polyethylene) and ion release.
  • These reactions are generally granulomatous foreign-body responses, not associated with prosthetic joint infections.

Purpose of the Study:

  • To report an unusual case of a fungal prosthetic joint infection presenting as a large inflammatory pseudotumor.
  • To highlight the potential for fungal infections, specifically Candida albicans, to manifest as pseudotumors in THA.

Main Methods:

  • Case report of a patient with a Candida albicans THA infection.
  • Clinical presentation and diagnostic considerations of fungal periprosthetic joint infections.

Main Results:

  • A large inflammatory pseudotumor of the hip joint was caused by Candida albicans infection.
  • Fungal periprosthetic joint infections are rare and diagnostically challenging.

Conclusions:

  • Pseudotumors can be a manifestation of fungal periprosthetic joint infections, contrary to common associations.
  • Fungal THA infections should be suspected in immunocompromised patients presenting with prosthetic joint infection symptoms.

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