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Pediatric mechanical circulatory support

Ivan Wilmot1, Angela Lorts1, David Morales2

  • 1Department of Cardiology, The Heart Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, USA.

The Korean Journal of Thoracic and Cardiovascular Surgery
|December 26, 2013
PubMed

Insights

Mechanical circulatory support (MCS) offers new hope for pediatric heart failure patients, especially infants and neonates. This review explores available short and long-term MCS options for children with end-stage heart failure.

Area of Science:

  • Pediatric Cardiology
  • Biomedical Engineering
  • Heart Failure Management

Background:

  • Pediatric heart failure, particularly in infants and neonates, is a growing concern with limited treatment history.
  • Children often present with end-stage heart failure, making traditional heart transplantation challenging due to delayed symptom onset.
  • Extracorporeal membranous oxygenation (ECMO) as a bridge to transplant has shown suboptimal outcomes in this population.

Purpose of the Study:

  • To review current mechanical circulatory support (MCS) options for pediatric end-stage heart failure.
  • To discuss the evolving landscape of MCS for infants and children awaiting heart transplantation or requiring chronic support.

Main Methods:

  • Literature review of available short-term and long-term mechanical circulatory support devices.
  • Analysis of current clinical practices and research in pediatric mechanical circulatory support.

Main Results:

  • Mechanical circulatory support (MCS) is increasingly recognized as a vital therapy for pediatric heart failure.
  • A growing number of MCS options are being developed for both bridge-to-transplant and destination therapy in children.
  • The focus is shifting towards developing more effective and sustainable MCS solutions for the pediatric population.

Conclusions:

  • Mechanical circulatory support (MCS) is crucial for managing pediatric end-stage heart failure, especially in neonates and infants.
  • The development of advanced MCS technologies is essential to improve outcomes for children with medically resistant heart failure.
  • Further research and innovation in pediatric MCS are needed to address the unmet needs in this vulnerable population.

Keywords:
Cardiac transplantationExtracorporeal membranous oxygenationHeart failurePediatricVentricular assist device

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