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Cryptogenic multifocal ulcerous stenosing enteritis: a review of the literature

Darina Kohoutová1, Jolana Bártová1, Ilja Tachecí1

  • 12nd Department of Internal Medicine-Gastroenterology, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, 500 05 Hradec Králové, Czech Republic.

Gastroenterology Research and Practice
|December 27, 2013
PubMed

Insights

Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare condition causing intestinal strictures and ulcers. Deep enteroscopy aids diagnosis and endoscopic treatment, potentially avoiding surgery.

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Digestive Diseases

Background:

  • Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare disorder.
  • It presents as chronic or relapsing subileus due to small intestinal strictures and ulcers.
  • The exact cause and pathogenesis remain unclear.

Purpose of the Study:

  • To highlight the diagnostic and therapeutic potential of deep enteroscopy in managing CMUSE.
  • To explore how deep enteroscopy can potentially reduce surgical interventions for CMUSE patients.

Main Methods:

  • Review of CMUSE characteristics and current treatment approaches.
  • Emphasis on the role and capabilities of deep enteroscopy in diagnosis and treatment.

Main Results:

  • Systemic glucocorticosteroids are the primary treatment but often lead to dependence.
  • Deep enteroscopy allows for precise diagnosis of strictures and ulcers.
  • Endoscopic treatment of stenoses is feasible with deep enteroscopy.

Conclusions:

  • Deep enteroscopy is a valuable tool for precise diagnosis in CMUSE.
  • Endoscopic interventions via deep enteroscopy may obviate the need for surgery.
  • This approach can help prevent extensive small bowel resections in CMUSE patients.

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