Diagnostic and Therapeutic Approach in a Patient with Buerger's and Coronary Artery Disease
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Updated: May 4, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Fotios Mitropoulos1, Fotios Eforakopoulos1, Meletios A Kanakis1
1Department of Pediatric and Congenital Heart Surgery, Onassis Cardiac Surgery Center, 356 Syngrou Avenue, 176 74 Kallithea, Greece.
Insights
Coronary artery disease coexisting with Buerger
Area of Science:
- Cardiology
- Vascular Surgery
Background:
- Buerger's disease, a rare inflammatory condition affecting blood vessels, rarely coexists with coronary artery disease.
- Patients with Buerger's disease often have compromised peripheral vasculature, complicating cardiovascular diagnostics and treatment.
Purpose of the Study:
- To report a rare case of coexisting coronary artery disease and Buerger's disease.
- To discuss diagnostic and therapeutic challenges in managing such patients.
Main Methods:
- Computed tomography (CT) angiography for coronary artery assessment.
- Off-pump coronary artery bypass grafting (CABG) for revascularization.
Main Results:
- CT angiography successfully diagnosed severe Left Anterior Descending (LAD) artery obstruction.
- Percutaneous coronary intervention was not feasible due to vascular status.
- Off-pump CABG was performed successfully, with an uncomplicated postoperative course.
Conclusions:
- CT angiography is a valuable tool for diagnosing coronary artery disease when conventional angiography is contraindicated.
- Off-pump CABG is a viable and effective therapeutic option for high-risk patients with coexisting Buerger's disease and coronary artery disease.
Abstract:
Occlusive coronary artery disease coexisting with Buerger's disease has rarely been reported. Potential difficulties regarding diagnostic workup and therapeutic management in this group of patients are discussed through this case report. We present an interesting case of a 52-year-old patient suffering from Buerger's disease, with a history of generalized peripheral occlusive arteriopathy, who presented with acute coronary syndrome. A difficulty in accessing and performing coronary angiography was evident due to the vascular status of the patient. Diagnosis was performed by computed tomography (CT) of the coronary arteries. It showed 80-90% obstruction of the LAD, and since percutaneous coronary intervention was impossible, a single aortocoronary bypass grafting was performed with the off-pump technique. Coronary artery disease coexisting with Burger's disease is a rare entity, and CT angiography is a useful diagnostic tool, when the classic angiography could not be performed. In addition, off-pump coronary artery bypass should be the therapeutic option of choice in this high risk group of patients. The uncomplicated postoperative course of the patient and his hitherto good condition showed that both diagnostic and therapeutic procedures were the best possible.
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