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Updated: May 4, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
Subarachnoid hemorrhage: beyond aneurysms
Carrie P Marder1, Vinod Narla, James R Fink
11 All authors: Department of Radiology, University of Washington, Box 357115, 1959 NE Pacific St, NW011, Seattle, WA 98195-7115.
Spontaneous subarachnoid hemorrhage (SAH) has diverse causes beyond ruptured aneurysms. CT scan patterns help differentiate SAH types and guide further investigation for accurate diagnosis.
Area of Science:
- Neurology
- Radiology
- Emergency Medicine
Background:
- Spontaneous subarachnoid hemorrhage (SAH) is commonly caused by ruptured saccular aneurysms.
- The differential diagnosis for SAH extends beyond aneurysms, especially based on clinical presentation and imaging findings.
Purpose of the Study:
- To classify SAH patterns based on CT findings.
- To guide differential diagnosis and subsequent imaging strategies for SAH.
- To review conditions that mimic SAH on imaging (pseudo-SAH).
Main Methods:
- Classification of SAH into three patterns based on unenhanced CT blood distribution: diffuse, perimesencephalic, and convexal.
- Analysis of hemorrhage epicenter to refine differential diagnosis.
- Review of clinical conditions causing pseudo-SAH.
Main Results:
- SAH can be categorized into diffuse, perimesencephalic, and convexal patterns on CT.
- Hemorrhage location is crucial for differential diagnosis and imaging guidance.
- Pseudo-SAH, mimicking SAH on CT/MRI, is a recognized imaging artifact.
Conclusions:
- CT-based classification of SAH patterns aids in diagnosis.
- Understanding hemorrhage distribution and epicenter is key for effective workup.
- Recognition of pseudo-SAH is important to avoid misdiagnosis.
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