Related Experiment Video
Updated: May 4, 2026
Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Current practice patterns for oral chemotherapy: results of a national survey
Janna C Roop1, Horng-Shiuann Wu1
1College of Nursing, Wayne State University, Detroit, MI.
Purpose/Objectives:
To describe current nursing practices in the United States regarding care and safety of patients taking oral chemotherapy.
Design:
This three-phase study consisted of development, validation, and implementation of a national online survey.
Setting:
Survey of oncology nurses in outpatient settings.
Sample:
577 oncology nurses.
Methods:
Surveys were emailed to 5,000 members of the Oncology Nursing Society. The survey included 17 forced-choice items and one free-text item. Descriptive statistics and content analysis were obtained.
Main Research Variables:
Patient care practices, nursing resources, and barriers to medication adherence.
Findings:
Fifty-one percent of the respondents worked in practices that had developed specific policies, procedures, and resources for patients on oral chemotherapy. Barriers to treatment adherence included cost (81%) and adverse effects (72%). Practices with specific policies differed in clinical and statistical significance from practices without policies on almost every survey item. Free-text responses revealed that many practices have erratic procedures and inadequate interdisciplinary communication.
Conclusions:
Systematic reliable policies and procedures for patient education, documentation, and interdisciplinary communication are urgently needed.
Implications For Nursing:
Nurses should provide education and repeated teaching to improve patient safety, adherence to the medication, and self-monitoring for adverse effects.
Related Concept Videos
01:27Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
01:28Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:49Cancer Therapies
01:23Oral Drug Delivery Systems: Introduction
01:27Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...