Eptifibatide induced profound thrombocytopenia in a patient with pelvic malignancy: A case report

Kathryn C Squires1, Saketh R Guntupalli1, Premal H Thaker1

  • 1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, Saint Louis, MO, USA.

► Eptifibatide is associated with profound thrombocytopenia and thrombosis secondary to a HITT-like mechanism associated with drug-dependant antibodies. ► Caution with eptifibatide use is needed in those pre-disposed to hypercoaguability, particularly those with an underlying malignancy.