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Detection of Aggregation-Prone Behavior in Mutant P53 V157F Breast Cancer Cells Using Multipoint Thioflavin T Fluorescence
Published on: December 30, 2025
Novel TP53 gene mutation and correlation with p53 immunohistochemistry in a mixed epithelial carcinoma of the
Andrew B Sholl1, Dara L Aisner2, Kian Behbakht3
1University of Colorado, Department of Pathology, USA ; MD Anderson Cancer Center, Department of Pathology, USA.
Abstract:
► We examine the correlation between p53 immunohistochemistry and TP53 gene mutation status in a mixed epithelial endometrial carcinoma. ► We describe a novel R306* (c.916C > T) mutation in exon 8 of the TP53 gene. ► We propose that the distinction between Type I and Type II endometrial carcinomas may be more fluid than previously believed.
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