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Updated: May 4, 2026

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
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Diphenyleneiodonium, an inhibitor of NOXes and DUOXes, is also an iodide-specific transporter

C Massart1, N Giusti1, R Beauwens2

  • 1IRIBHM, School of Medicine, ULB, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, Belgium.

FEBS Open Bio
|December 28, 2013
PubMed

Keywords:
DPI, diphenyleneiodoniumDUOXDUOXes, dual oxidasesDiphenyleneiodoniumHRP, horse radish peroxidase type IIHVA, homovanillic acidIodide effluxKRH, Krebs–Ringer Hepes mediumMMI, methylmercaptoimidazoleNIS, sodium/iodide symporterNOXNOXes, NADPH oxidasesO2 radical generationThyroid

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