Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tanorexia: The psychodermatology of compulsive tanning.

Clinics in dermatology·2026
Same author

Deep Learning vs. Traditional Machine Learning in the Diagnosis of Cutaneous Drug Eruptions: A Comparative Study with Explainable AI on Whole-Slide Images.

Journal of imaging informatics in medicine·2026
Same author

Occupational Risk of Sexually Transmitted Infections in Aesthetic Dermatology and Dermatologic Surgery: Evidence and Prevention.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same author

Sleep quality in patients with mycosis fungoides and its relationship with dermatology-specific quality of life.

Clinics in dermatology·2026
Same author

Age-related histopathological and immunophenotypic variations in early-stage mycosis fungoides: a multicentre retrospective study in Türkiye.

BMJ open·2026
Same author

Persona non grata: Identifying patients unsuitable for aesthetic dermatologic procedures.

Clinics in dermatology·2026

Related Experiment Video

Updated: May 4, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
11:12

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

7.8K

Microchimerism in Behçet's disease.

Ruken Alp1, Aysequl U Guney, Umit Tursen

  • 1Department of Dermatology, Mersin University, Mersin, Turkey.

International Journal of Dermatology
|December 31, 2013
PubMed
Summary
This summary is machine-generated.

Microchimerism, the presence of fetal DNA, may play a role in Behçet's disease (BD) pathogenesis. This study found a significant association between microchimerism and BD in women, suggesting further research is needed.

More Related Videos

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
11:25

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice

Published on: April 1, 2015

13.1K
Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

6.8K

Related Experiment Videos

Last Updated: May 4, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
11:12

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

7.8K
Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
11:25

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice

Published on: April 1, 2015

13.1K
Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

6.8K

Area of Science:

  • Immunology
  • Genetics
  • Rheumatology

Background:

  • Behçet's disease (BD) is a multisystemic autoimmune disorder of unknown cause.
  • Immunological dysfunction is a key factor in BD pathogenesis.
  • Microchimerism, the presence of allogeneic DNA, is being investigated in autoimmune diseases.

Purpose of the Study:

  • To investigate the potential role of microchimerism in the etiopathogenesis of Behçet's disease.
  • To determine if fetal microchimerism is associated with BD in women.

Main Methods:

  • The SRY gene was analyzed as an indicator of fetal microchimerism.
  • 105 women diagnosed with BD were compared to healthy female controls.
  • Patients and controls were grouped based on whether they had given birth to a son.

Main Results:

  • The SRY gene, indicating microchimerism, was detected in 75.9% of BD patients.
  • Only 3.9% of the control group showed the presence of the SRY gene.
  • The difference in SRY gene presence between BD patients and controls was statistically significant (P < 0.001).

Conclusions:

  • Microchimerism may be associated with the development of Behçet's disease.
  • Further studies with larger cohorts are required to confirm this association.
  • This finding contributes to understanding the autoimmune mechanisms underlying BD.