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Related Concept Videos

Gene Therapy00:59

Gene Therapy

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Related Experiment Video

Updated: May 4, 2026

Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells
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Gene therapy.

B J Baum1

  • 1Gene Transfer Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD, USA.

Oral Diseases
|December 31, 2013
PubMed
Summary
This summary is machine-generated.

Gene therapy shows promise for oral tissues, with successful animal model results. Oral medicine practitioners should monitor this novel treatment for future patient benefits in oral diseases.

Keywords:
gene therapymouthoral diseases

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Area of Science:

  • Biomedical Science
  • Regenerative Medicine
  • Oral Biology

Background:

  • Gene therapy applications are being explored across all oral tissues.
  • Significant success has been observed in preclinical animal models.

Purpose of the Study:

  • To review the current state and potential of gene therapy in oral medicine.
  • To inform oral medicine practitioners about emerging therapeutic strategies.

Main Methods:

  • Literature review of gene therapy studies in oral tissues.
  • Analysis of successful applications in animal models.

Main Results:

  • Gene therapy has demonstrated efficacy in various oral tissue models.
  • Many applications have shown positive outcomes in preclinical research.

Conclusions:

  • Gene therapy is a promising novel treatment for oral diseases.
  • While not yet routine, awareness is crucial for future clinical practice.
  • This approach is expected to benefit numerous patients with oral conditions.