[Follicular dendritic cell sarcoma in head and neck region]

Area of Science:

• Oncology
• Surgical Pathology
• Head and Neck Cancer

Background:

• Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm with uncertain lineage, exhibiting features of both lymphoma and sarcoma.
• Optimal treatment strategies for FDCS remain controversial due to its rarity and biphenotypic nature.

Observation:

• Two cases of head and neck FDCS were treated.
• The patients experienced favorable outcomes following surgical resection and radiotherapy.

Findings:

• Histopathological analysis is crucial for accurate diagnosis and differentiation from other tumors.
• Combined modality treatment including surgery and radiotherapy can lead to favorable outcomes in head and neck FDCS.

Implications:

• This case series contributes to understanding the clinical behavior of FDCS in the head and neck region.
• The findings support a multimodal treatment approach for FDCS, potentially improving patient prognosis.
• Further research is warranted to establish standardized treatment guidelines for follicular dendritic cell sarcoma.