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Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography
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Neurogenic stress cardiomyopathy in heart donors

Burhan Mohamedali1, Geetha Bhat1, Antone Tatooles1

  • 1Division of Cardiology and Cardiovascular Surgery, Advocate Christ Medical Center, University of Illinois Hospitals and Health Sciences System, Chicago and Oak Lawn, Illinois.

Journal of Cardiac Failure
|December 31, 2013
PubMed

Insights

Donor heart availability for transplantation is limited. Neurogenic stress cardiomyopathy can cause left ventricular dysfunction, complicating donor heart procurement. This case highlights successful heart procurement despite severe dysfunction.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Neurology

Background:

  • Donor availability significantly limits cardiac transplantation worldwide.
  • Neurogenic stress cardiomyopathy (NSC) frequently complicates donor evaluation, posing a procurement challenge.
  • Left ventricular dysfunction is a common presentation of NSC.

Observation:

  • A case of a 23-year-old male donor with severe left ventricular dysfunction is presented.
  • The donor heart was successfully procured for transplantation despite the observed dysfunction.
  • This case underscores the potential for successful organ procurement in challenging scenarios.

Findings:

  • Severe left ventricular dysfunction in a donor is not an absolute contraindication for cardiac transplantation.
  • Successful heart procurement was achieved, enabling transplantation.
  • The report includes a comprehensive review of NSC and donor evaluation protocols.

Implications:

  • This case may broaden criteria for donor heart acceptance.
  • Improved understanding of NSC can optimize donor evaluation and increase organ availability.
  • Successful transplantation from donors with prior left ventricular dysfunction offers hope for more recipients.

Keywords:
Neurogenic stress cardiomyopathycardiac transplantdonor evaluationheart transplant

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