Sorafenib in renal cell carcinoma
Ehsan Taghizadeh Davoudi1, Mohamed Ibrahim bin-Noordin1, Hamid Akbari Javar2
1Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Renal cell carcinoma (RCC) is a complex cancer. This review details advancements in targeted therapies, highlighting Sorafenib as a key agent for improved treatment outcomes.
Area of Science:
- Oncology
- Pharmacology
Background:
- Renal cell carcinoma (RCC) is a significant cause of cancer mortality.
- RCC presents complex pathophysiology and treatment challenges compared to other cancers.
Purpose of the Study:
- To provide an overview of renal cell carcinoma.
- To offer insights into the development of targeted therapies for RCC.
- To review the clinical development of Sorafenib for RCC treatment.
Main Methods:
- Comprehensive review of hundreds of research papers and published works.
- Focus on key aspects of renal cell carcinoma, its treatment, and Sorafenib's development.
Main Results:
- Sorafenib represents a significant advancement in targeted therapy for RCC.
- The study highlights progress in developing more effective agents for complex cancers.
Conclusions:
- Continued research and development are crucial for combating complex cancers like RCC.
- Targeted therapies like Sorafenib offer a promising future in cancer treatment.
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