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Related Experiment Video

Updated: May 4, 2026

Biolistic Transformation of a Fluorescent Tagged Gene into the Opportunistic Fungal Pathogen Cryptococcus neoformans

Biolistic Transformation of a Fluorescent Tagged Gene into the Opportunistic Fungal Pathogen Cryptococcus neoformans

Published on: March 19, 2015

Cryptococcus neoformans: historical curiosity to modern pathogen.

Deepa Srikanta¹, Felipe H Santiago-Tirado, Tamara L Doering

¹Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.

Yeast (Chichester, England)

|December 31, 2013

Summary

Cryptococcus neoformans, a fungus impacting human health, is a key model for studying physiology and disease. Research explores its biology, virulence, and available study tools.

Keywords:

Cryptococcus gattii Cryptococcus neoformans capsule cryptococcosis meningitis pathogenic fungus yeast

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Biolistic Transformation of a Fluorescent Tagged Gene into the Opportunistic Fungal Pathogen Cryptococcus neoformans

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Published on: March 19, 2015

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Size Matters: Measurement of Capsule Diameter in Cryptococcus neoformans

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Area of Science:

Mycology
Pathogenesis research
Fungal biology

Background:

Cryptococcus neoformans is a significant human pathogen.
Its importance necessitates its use as an experimental model.
Studying this fungus aids understanding of basic physiology and disease.

Observation:

This review covers the history of Cryptococcus neoformans research.
Notable virulence factors are discussed.
Current experimental tools for studying the fungus are presented.

Findings:

The review highlights key biological aspects contributing to Cryptococcus neoformans virulence.
It provides an overview of established and emerging research methodologies.
The versatility of this fungus as a model organism is emphasized.

Implications:

Understanding Cryptococcus neoformans biology can lead to novel therapeutic strategies.
This research informs the development of new diagnostic and treatment tools.
The study of fungal pathogens like C. neoformans is crucial for public health.