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Published on: November 11, 2021
Neuroblastoma and pediatric delirium: a case series
Chani Traube1, Julie Augenstein, Bruce Greenwald
1Division of Pediatric Critical Care Medicine, Weill Cornell Medical College, New York, New York.
Insights
Delirium is common in critically ill children, especially those with neuroblastoma. Early diagnosis and intervention in these pediatric cancer patients can improve outcomes.
Area of Science:
- Pediatric critical care medicine
- Pediatric oncology
- Neuroscience
Background:
- Delirium is a frequent complication in critically ill children.
- Children with neuroblastoma are identified as a high-risk group for delirium.
- Early detection and management of delirium are crucial for improving patient outcomes.
Purpose of the Study:
- To present a case series of critically ill children with neuroblastoma diagnosed with delirium.
- To highlight the impact of delirium diagnosis on treatment and patient improvement.
- To emphasize the importance of increased awareness among healthcare professionals for earlier diagnosis and better outcomes.
Main Methods:
- Case series methodology.
- Inclusion of four critically ill children diagnosed with neuroblastoma and delirium.
- Observation of clinical course and response to interventions post-diagnosis.
Main Results:
- All four patients diagnosed with delirium showed improvement following targeted interventions.
- The diagnosis of delirium was instrumental in guiding appropriate management strategies.
- The case series demonstrates a positive correlation between delirium diagnosis and clinical improvement.
Conclusions:
- Critically ill children with neuroblastoma are susceptible to delirium, particularly post-operatively.
- Prompt diagnosis of delirium in this population facilitates effective interventions.
- Enhanced awareness and collaboration among pediatric oncologists, surgeons, and intensivists can improve clinical outcomes for these patients.
Abstract:
Delirium occurs frequently in critically ill children, and children with neuroblastoma may be at particular risk. Early diagnosis and treatment may improve short- and long-term outcomes. In this case series, we present four critically ill children with neuroblastoma who were diagnosed with delirium in the post-operative period. In all four patients, the diagnosis of delirium facilitated targeted intervention and improvement. Heightened awareness by pediatric oncologists, surgeons, and intensivists may lead to earlier diagnosis and improvement in clinical outcomes.
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