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Primary angiosarcoma of bone. A case report.

A Baliaka1, Gc Balis1, E Michalopoulou-Manoloutsiou1

  • 1Department of Pathology, Cancer Hospital of Thessaloniki "Theagenio"

Hippokratia
|December 31, 2013
PubMed
Summary
This summary is machine-generated.

Primary angiosarcoma of bone is a rare, aggressive vascular tumor. This case highlights a pathological hip fracture in a male patient, leading to diagnosis and treatment with radiotherapy and surgery.

Keywords:
Primary angiosarcomabonevascular tumor

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Area of Science:

  • Oncology
  • Orthopedic Surgery
  • Vascular Tumors

Background:

  • Primary malignant vascular tumors of bone are exceptionally rare, comprising less than 1% of bone malignancies.
  • Angiosarcoma, an aggressive vascular tumor, originates from mesenchymal cells with endothelial differentiation.

Observation:

  • A 47-year-old male experienced a pathological intertrochanteric hip fracture during transport post-lumbar disk herniation surgery.
  • Magnetic resonance imaging (MRI) identified a lytic bone lesion in the right femur's great trochanter.

Findings:

  • Open surgical biopsy confirmed primary angiosarcoma of bone.
  • Histological examination of the surgical specimen validated the diagnosis.

Implications:

  • The case underscores the importance of considering rare bone tumors in fracture etiology.
  • Multimodal treatment involving radiotherapy and surgical reconstruction (hip arthroplasty) can be effective for bone angiosarcoma.