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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

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Langerhans cell sarcoma: Response to radiotherapy.

Anna Lucas¹, Eva González Barca², Octavio Servitje³

¹Department of Radiation Oncology, Institut Català d'Oncologia, L'Hospitalet, Barcelona, Spain.

Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

|December 31, 2013

Summary

Palliative radiotherapy effectively managed progressive Langerhans cell sarcoma, including skin lesions and lymph node masses. Low radiation doses provided good and lasting symptom relief, suggesting a recommended 15-30 Gy range.

Keywords:

Langerhans cell sarcoma Radiotherapy

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Published on: April 22, 2019

Area of Science:

Oncology
Radiotherapy
Dermatology

Background:

Langerhans cell sarcoma is a rare malignancy.
Cutaneous and nodal involvement presents significant treatment challenges.

Purpose of the Study:

To evaluate the efficacy of palliative radiotherapy for Langerhans cell sarcoma.
To determine optimal radiation dosing for symptom management.

Main Methods:

Case presentation of a patient with progressive Langerhans cell sarcoma.
Treatment with palliative radiotherapy for cutaneous lesions and nodal masses.

Main Results:

Achieved good and sustained response to relatively low doses of radiotherapy.
Demonstrated effective palliation of symptoms associated with the disease.

Conclusions:

Palliative radiotherapy is a viable treatment option for Langerhans cell sarcoma.
A recommended dose of 15-30 Gy is suggested, adjusted for treatment goals and lesion size.