Related Experiment Video
Updated: May 4, 2026

09:30
Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
Published on: March 4, 2016
20.9K
Suction blister skin grafting--a modern application.
1Bedfordshire, Hertfordshire & Buckinghamshire Network, Luton & Dunstable University Hospital NHS Foundation Trust, Lewsey Road, Luton, Bedford LU4 0DZ, United Kingdom.
The British Journal of Oral & Maxillofacial Surgery
|January 1, 2014
Summary
The suction blistering technique offers a non-invasive method for creating ultra-thin skin grafts. This approach ensures excellent graft survival and no donor site morbidity, making it ideal for complex reconstructive surgery.
Area of Science:
- Regenerative Medicine
- Dermatology
- Plastic Surgery
Background:
- Traditional skin grafting can involve donor site morbidity.
- Reconstruction in patients with poor vascularity or comorbidities presents challenges.
- Previous reconstructions may fail, necessitating alternative approaches.
Purpose of the Study:
- To evaluate the efficacy of the suction blistering technique for skin grafting.
- To assess graft survival and donor site morbidity.
- To determine the utility of this technique in challenging reconstructive scenarios.
Main Methods:
- Utilizing negative pressure via wall suction to generate ultra-thin skin grafts in an outpatient setting.
- Applying the harvested grafts for reconstruction, including over Integra® dermal regeneration template.
- Assessing graft survival and donor site healing post-procedure.
Main Results:
- Achieved over 95% graft survival by surface area in a patient with prior failed reconstructions.
- Demonstrated no donor site morbidity.
- Observed excellent graft take and rapid donor site healing, particularly over Integra®.
Conclusions:
- Suction blistering is a valuable, minimally invasive technique for obtaining ultra-thin skin grafts.
- The method is well-tolerated, provides excellent graft survival, and avoids donor site complications.
- It is particularly advantageous for reconstructions in patients with poor recipient vascularity or significant comorbidities.

