Related Experiment Video
Updated: May 4, 2026
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Expression of EGFR and p53 in head and neck tumors among Sudanese patients
Mustafa Saadalnour Abusail1, Ahmed Mohmed Ahmed Dirweesh, Rashid Awad Abdalla Salih
1Department of Histopathology and Cytology, Faculty of Medical laboratory Sciences, Elneelain University, Sudan E-mail : Hussaingad1972@yahoo.com, he.ahmed@uoh.edu.sa.
Background:
The aim of this study was to assess EGFR and p53 expression in head and neck tumors among Sudanese patients using immunohistochemistry.
Materials And Methods:
A retrospective descriptive study was performed on 150 samples from patients diagnosed with HNCs as well as 50 from individuals with benign head and neck tumors. EGFR and p53 expression was assessed using immunohistochemistry (IHC).
Results:
EGFR was expressed in 126/150 (84%) of HNCS and 6/50 (12%) benign head and neck tumors where as p53 was expressed in 29/150 (19.3%) of HNCs and 2/50 (4%) of benign head and neck tumors, with significance at p values of 0.001 and 0.009 respectively.
Conclusions:
There is a significant association between EGFR, P53 expression and head and neck cancers among Sudanese patients.
