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Updated: May 4, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
A simple framework to generate 3D patient-specific model of coronary artery bifurcation from single-plane
Ferdinando Auricchio1, Michele Conti2, Carolina Ferrazzano3
1Dipartimento di Ingegneria Civile e Architettura, Università degli Studi di Pavia, via Ferrata 1, 27100 Pavia, Italy; CESNA - Centro di Simulazione Numerica Avanzata, Pavia, Italy; IUSS - Istituto Universitario degli Studi Superiori di Pavia, Piazza della Vittoria 15, 27100 Pavia, Italy.
Abstract:
Although computer-based simulations, such as structural finite element analysis, have proven their usefulness to support procedural planning of coronary stenting, the link between the clinical practice and these engineering techniques is still limited to research test-cases. A key point to further promote such an interaction is to generate in a fast and effective manner the computational grids from the medical images. Hence, the present study proposes a simple framework to generate 3D meshes of coronary bifurcations from a pair of planar angiographic images obtained by X-ray angiography, which is the gold standard technique for the diagnosis of coronary artery stenosis.

