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Parent-reported sleep problems, symptom ratings, and serum ferritin levels in children with
Maha K Abou-Khadra1, Omnia R Amin, Olfat G Shaker
1Department of Pediatrics, Faculty of Medicine, Cairo University, 2 Yousef Fahmy Street, El-Areech Street, Al-Ahram Street, Giza, Egypt. maha_korany71@yahoo.com.
Insights
Children with attention-deficit/hyperactivity disorder (ADHD) experience frequent sleep problems. This study found that lower serum ferritin levels in children with ADHD are linked to more significant sleep disturbances.
Area of Science:
- Pediatric Neurology
- Sleep Medicine
- Nutritional Psychiatry
Background:
- Sleep disturbances are prevalent in children diagnosed with attention-deficit/hyperactivity disorder (ADHD).
- Serum ferritin levels have been previously linked to ADHD symptom severity and sleep issues.
Purpose of the Study:
- To investigate parent-reported sleep problems in Egyptian children with ADHD.
- To examine the relationship between sleep, ADHD symptom ratings, and serum ferritin levels.
Main Methods:
- Utilized the Children's Sleep Habits Questionnaire (CSHQ) and Conners' Parent Rating Scale-Revised (CPRS-R:L).
- Measured serum ferritin levels via enzyme-linked immunosorbent assay in 41 children with ADHD (aged 6-12) and 62 controls.
Main Results:
- ADHD group exhibited significantly higher CSHQ scores.
- Children with serum ferritin <30 ng/mL reported more disturbed sleep.
- Found negative correlations between sleep duration, total CSHQ score, and serum ferritin levels.
Conclusions:
- Sleep problems are common in children with ADHD.
- Low serum ferritin levels are associated with increased sleep disturbances in this population.
Background:
Sleep problems are common among children with attention-deficit/hyperactivity disorder (ADHD). Serum ferritin levels have been associated with the severity of symptoms and sleep disturbances among children with ADHD. This study was conducted to investigate parent-reported sleep problems in a sample of Egyptian children with ADHD and to examine the relationship between their sleep, symptom-ratings, and low serum ferritin levels.
Methods:
Parents of 41 ADHD children, aged 6 to 12 years, filled out the Children's Sleep Habits Questionnaire (CSHQ) and Conners' Parent Rating Scale-Revised: Long Version (CPRS-R:L) in Arabic. Serum ferritin levels were determined with an enzyme-linked immunosorbent assay. The parents of the 62 controls filled out the CSHQ.
Results:
The ADHD group showed significantly higher scores in CSHQ subscales and total score. Children with serum ferritin levels <30 ng/mL had more disturbed sleep. There were significant negative correlations between sleep duration subscale, total score of CSHQ, and serum ferritin levels. There were no significant differences in hyperactivity, cognitive problems/inattention, oppositional, or ADHD index subscale scores between children with serum ferritin levels <30 ng/mL and those with serum ferritin levels ≥ 30 ng/mL.
Conclusions:
Sleep problems are common, and this study suggests an association between low serum ferritin levels and sleep disturbances.
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