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TGFβ in endosomal signaling.

Sarah McLean1, Gianni M Di Guglielmo2

  • 1Department of Anatomy and Cell Biology, Western University, London, Ontario, Canada; Department of Physiology and Pharmacology, Western University, London, Ontario, Canada.

Methods in Enzymology
|January 1, 2014
PubMed
Summary

Transforming growth factor beta (TGFβ) receptor trafficking impacts cell signaling. This chapter details methods for isolating membrane rafts and tracking TGFβ receptor movement to understand signal transduction outcomes.

Keywords:
Immunofluorescence microscopyMembrane raftsReceptor internalizationSubcellular fractionationTransforming growth factor beta

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