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[Patient with acute renal injury presenting dabigatran overdose: Hemodialysis for surgery]

B Bachellerie1, S Ruiz1, J-M Conil1

  • 1Pôle d'anesthésie réanimation, hôpital de Rangueil, 31059 Toulouse cedex 9, France.

Annales Francaises D'Anesthesie Et De Reanimation
|January 1, 2014
PubMed

Dabigatran is a direct thrombin inhibitor indicated for stroke and systemic embolism prevention in patients with non-valvular atrial fibrillation. No reversal agent exists, but hemodialysis has been proposed as dabigatran removal method. We report a case of an 80-year-old man presenting hemorrhage with dabigatran overdose caused by obstructive acute renal failure. Before nephrostomy, several hemodialysis sessions were necessary to remove dabigatran probably because of its large volume of distribution.

Keywords:
Acute renal injuryDabigatranHemodialysisHémodialyseHémorragieInsuffisance rénale aiguëOverdoseSurdosage

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