Related Experiment Video
Updated: May 4, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
Published on: May 3, 2018
Arterial pressure: agreement between a brachial cuff-based device and radial tonometry
Chloe M Park1, Olga Korolkova, Justin E Davies
1aInternational Centre for Circulatory Health, Imperial College London & Imperial College Healthcare NHS Trust bDepartment of Bioengineering, Imperial College London, London, UK.
A new noninvasive cuff-based device accurately estimates central blood pressure (BP), offering a simpler alternative to current methods. This innovation could increase the clinical use of central BP measurements for better cardiovascular risk prediction.
Area of Science:
- Cardiovascular research
- Biomedical engineering
- Clinical diagnostics
Background:
- Aortic (central) blood pressure (BP) measurement is a superior predictor of cardiovascular events compared to brachial BP.
- Current central BP measurement methods are often restricted to research settings due to operator dependency.
Purpose of the Study:
- To evaluate a novel noninvasive cuff-based device for estimating central BP.
- To compare the device's accuracy against radial tonometry and invasive aortic BP measurements.
Main Methods:
- 1107 individuals underwent cuff-based and tonometry-based central BP estimation.
- Reproducibility was assessed in 28 individuals.
- Simultaneous cuff-based and invasive pressure traces were compared in six individuals.
Main Results:
- The cuff-based device demonstrated high reproducibility for central systolic BP.
- Estimates were comparable to tonometry (average difference 3 ± 6 mmHg).
- Cuff-based pressure waveforms closely matched invasive measurements (cross-correlation 0.93).
Conclusions:
- Noninvasive cuff-based devices show potential for simplifying central BP measurement.
- The device maintains fidelity comparable to tonometry.
- This technology could enhance the clinical adoption of central BP estimates.
Related Concept Videos
Sites for measuring blood pressure
The Brachial Artery: Primary Site for Blood Pressure Measurement
Assessment of blood pressure in brachial artery(two-step method)
Measurement of Blood Pressure
Assessment of blood pressure in brachial artery(one-step method)
Prepare for the Procedure:
Equipments Used To Measure Blood Pressure
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.

