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Published on: September 20, 2018
[Wernicke encephalopathy accompanying linitis plastica]
Zsuzsanna Soós1, Mónika Salamon1, Roland Oláh1
1Szent János Kórház II. Belgyógyászat-Diabetológia Budapest Diós árok 1-3. 1125.
Wernicke encephalopathy, a neurological disorder from vitamin B1 deficiency, often presents subtly. Early diagnosis is crucial, especially in cancer patients, to prevent severe outcomes.
Area of Science:
- Neurology
- Nutritional Neuroscience
Background:
- Wernicke encephalopathy (WE) is a neurological disorder caused by vitamin B1 deficiency.
- While classically presenting with a triad of confusion, oculomotor disturbance, and ataxia, confusion is the most common symptom.
- WE is frequently associated with chronic alcohol consumption but also occurs in other conditions, including advanced malignant diseases.
Observation:
- The authors report a case of an elderly male patient with advanced gastric cancer.
- This patient was diagnosed with and treated for vitamin B1 deficiency.
Findings:
- The case highlights the diagnostic challenges of Wernicke encephalopathy, particularly in non-alcoholic patients.
- Confusion in advanced cancer patients may indicate underlying vitamin B1 deficiency.
Implications:
- Increased awareness of WE is needed in patients with advanced cancers.
- Timely vitamin B1 supplementation can prevent severe neurological sequelae.
- This case underscores the importance of considering nutritional deficiencies in complex medical presentations.
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