[Transcutaneous penetration of a mucopolysaccharide polysulfuric acid ester in the human. A histochemical study]

Using a histochemical test method it was investigated whether a mucopolysaccharide polysulfuric acid ester (MPS, Hirudoid) is able to penetrate the human skin. The penetration of MPS into the corium and the subcutis was demonstrated by metachromatic staining of cells which store MPS, whereby cellular elements acquire a colour which is distinct from the staining solution, as soon as they have incorporated MPS.