Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.8K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.8K
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

2.5K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
2.5K
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

102
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
102
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

782
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
782
Atypical Pneumonia01:14

Atypical Pneumonia

84
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
84
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.7K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endocarditis Presenting as Arthritis With Positive Autoantibodies Mimicking Rheumatoid Arthritis.

International journal of rheumatic diseases·2025
Same author

Isolated Cerebellar Involvement in X-linked Adrenoleukodystrophy.

Annals of Indian Academy of Neurology·2021
Same author

Kikuchi-Fujimoto disease with multiple extra-nodal features - A clinical mimic.

Reumatismo·2019
Same author

A imported case of <i>Plasmodium malariae</i>.

Journal of postgraduate medicine·2018
Same author

A rare form of anemia in systemic lupus erythematosus.

Reumatismo·2017
Same author

Massive cerebral infarct due to Trousseau's syndrome in gastric cancer.

The Indian journal of medical research·2017
Same journal

Functional Outcomes and Complications of Dual Mobility Versus Fixed-Bearing Total Hip Arthroplasty in Femoral Neck Fractures over 55 Years: A Retrospective Analysis.

Indian journal of orthopaedics·2026
Same journal

Prevalence of Atherosclerosis in Femoral and Popliteal Arteries in Advanced Osteoarthritis Knee: A Cross Sectional Ultrasound Study.

Indian journal of orthopaedics·2026
Same journal

Efficacy of Pre-operative Physical Therapy on Total Knee Replacements: A Systematic Review of Randomized Controlled Trials.

Indian journal of orthopaedics·2026
Same journal

Predictive Value of Radiographs in Assessment of Post-Hemiarthroplasty Recovery Following Femoral Neck Fractures Amongst the Elderly.

Indian journal of orthopaedics·2026
Same journal

Reoperation Rates Following Lumbar Decompression Surgery at Three or More Levels.

Indian journal of orthopaedics·2026
Same journal

Morphological Analysis of Thoracolumbar Vertebrae Based on Age and Gender in Indonesia Population: A Computed Tomography-Based Study.

Indian journal of orthopaedics·2026
See all related articles

Related Experiment Video

Updated: May 4, 2026

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
09:57

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Published on: February 14, 2011

11.4K

Disseminated histoplasmosis.

C A Mansoor1, P V Bhargavan1, R Rajanish2

  • 1Department of General Medicine, M.E.S. Medical College, Perinthalmanna, Kerala, India.

Indian Journal of Orthopaedics
|January 1, 2014
PubMed
Summary
This summary is machine-generated.

Disseminated histoplasmosis can mimic tuberculosis and other granulomatous diseases. Early diagnosis through fungal staining is crucial for effective treatment, even in immunocompetent individuals.

Keywords:
Disseminated histoplasmosisgranulomatous diseaseimmune-competent

More Related Videos

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
09:02

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

Published on: February 17, 2014

21.3K
Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

12.7K

Related Experiment Videos

Last Updated: May 4, 2026

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
09:57

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Published on: February 14, 2011

11.4K
An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
09:02

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

Published on: February 17, 2014

21.3K
Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

12.7K

Area of Science:

  • Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Disseminated histoplasmosis is a severe fungal infection.
  • It often presents with non-specific symptoms, mimicking other granulomatous conditions like tuberculosis.
  • Delayed diagnosis can lead to prolonged, ineffective treatments.

Purpose of the Study:

  • To highlight a case of disseminated histoplasmosis.
  • To emphasize the importance of considering fungal infections in granulomatous diseases.
  • To underscore the diagnostic challenges and treatment implications.

Main Methods:

  • Case report of a 48-year-old male with a history of presumed granulomatous infection.
  • Review of previous unsuccessful treatments with anti-tubercular drugs.
  • Microscopic examination of fresh biopsies with fungal staining.

Main Results:

  • Disseminated histoplasmosis was identified via fungal staining in biopsies.
  • The patient had a prolonged, undiagnosed illness with subcutaneous swellings, ulcerations, and fever.
  • Previous treatments for presumed tuberculosis were ineffective.

Conclusions:

  • Fungal infections, such as disseminated histoplasmosis, should be considered in the differential diagnosis of granulomatous diseases.
  • Diagnostic procedures should include fungal stains, especially in cases with inadequate response to standard treatments.
  • This is important even in immunocompetent patients presenting with disseminated granulomatous infections.