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Ophthalmic Drug Delivery Systems01:23

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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
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Evaluating a new surgical dosage calculation method for esotropia.

Siddharth Agrawal1, Vinita Singh1, Sanjiv Kumar Gupta1

  • 1Department of Ophthalmology, King Georges' Medical University, Lucknow, Uttar Pradesh, India.

Oman Journal of Ophthalmology
|January 1, 2014
PubMed
Summary
This summary is machine-generated.

A simplified surgical method for correcting esotropia in children and adults proved highly accurate, with 91% success. This approach offers a predictable way to adjust eye alignment, reducing surgical outcome variations.

Keywords:
Esotropiarecessionresectionsurgical dosage

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Area of Science:

  • Ophthalmology
  • Strabismus Surgery
  • Pediatric Ophthalmology

Background:

  • Esotropia, a common ocular deviation, requires precise surgical correction.
  • Existing methods for calculating surgical dosage can lead to variable outcomes.
  • Infantile and acquired basic esotropia present unique challenges in surgical planning.

Purpose of the Study:

  • To evaluate a simplified, predictable method for surgical correction of ocular deviation in esotropia patients.
  • To assess the accuracy of a new normogram for unilateral recession-resection surgery.
  • To determine the efficacy of a simplified dosage calculation for medial rectus (MR) recession.

Main Methods:

  • Thirty-six patients with infantile and acquired basic esotropia underwent unilateral recession-resection surgery.
  • Surgical dosage was determined using a simplified normogram based on patient age and preoperative deviation.
  • Medial rectus (MR) recession and lateral rectus (LR) resection amounts were standardized based on age and deviation.

Main Results:

  • The simplified calculation method achieved a success rate of 91% (33 out of 36 patients).
  • The ratio of achieved to expected correction fell within the 0.9-1.1 range for most patients.
  • Statistical analysis showed the method's predictability in surgical outcomes.

Conclusions:

  • A simplified surgical dosage calculation method using MR recession is predictable for infantile and basic esotropia.
  • This approach can minimize variability in surgical results for strabismus correction.
  • The simplified method offers a reliable tool for ophthalmic surgeons treating esotropia.