Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cerebral Edema ll: Pathophysiology

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...

Cerebral Edema l: Introduction

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...

Cushing Syndrome II: Pathophysiology

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features...

Encephalitis l: Introduction

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

Cerebrospinal Fluid

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain....

Viral Meningitis

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Imaging Findings of Nodular Fasciitis in Breast including Artificial Intelligence Mammography and Shear Wave Elastography: A Case Report.

Journal of the Korean Society of Radiology·2023

Same author

Imaging Findings of Axillary Granular Cell Tumor in a Patient with Breast Cancer History: A Case Report.

Journal of the Korean Society of Radiology·2023

Same author

Immunoglobulin G4-related Disease of the Small Bowel: A Case of Long-term Remission Achieved by Surgical Resection without Maintenance Therapy.

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·2023

Same author

Imaging Findings of Breast Metastasis from Malignant Peripheral Nerve Sheath Tumor of Mediastinum: A Case Report.

Journal of the Korean Society of Radiology·2023

Same author

Gastric Inverted Polyps-Distinctive Subepithelial Lesions of the Stomach: Clinicopathologic Analysis of 12 Cases With an Emphasis on Neoplastic Potential.

The American journal of surgical pathology·2021

Same author

Gastric crystal-storing histiocytosis with concomitant mucosa-associated lymphoid tissue lymphoma.

Journal of pathology and translational medicine·2020

Search research articles

Related Experiment Video

Updated: May 4, 2026

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

Lymphomatosis cerebri.

Chan-Young Choi¹, Chae-Heuck Lee¹, Mee Joo²

¹Department of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea.

Journal of Korean Neurosurgical Society

|January 1, 2014

Summary

This summary is machine-generated.

Lymphomatosis cerebri, a rare diffuse primary central nervous system lymphoma, is often misdiagnosed. Early biopsy is crucial for accurate diagnosis and improved patient outcomes in this challenging condition.

Keywords:

Biopsy Lymphomatosis cerebri Primary central nervous system lymphoma

More Related Videos

Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research

Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research

Published on: March 29, 2024

Related Experiment Videos

Last Updated: May 4, 2026

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research

Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research

Published on: March 29, 2024

Area of Science:

Neuropathology
Neuro-oncology
Neuroradiology

Background:

Lymphomatosis cerebri is a rare, diffuse variant of primary central nervous system lymphoma.
It is frequently misdiagnosed due to overlapping symptoms with other neurological conditions.

Observation:

The case presented with rapid neurological deterioration, highlighting the aggressive nature of the disease.
Differential diagnoses considered included infiltrating tumors, degenerative disorders, ischemic diseases, and infectious diseases.

Findings:

Accurate diagnosis requires a high index of suspicion and prompt neuroimaging.
Histopathological confirmation via early biopsy is essential for definitive diagnosis.

Implications:

Increased awareness among clinicians can improve early recognition of lymphomatosis cerebri.
Timely diagnosis and appropriate treatment can prevent irreversible neurological damage and improve prognosis.