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Updated: May 4, 2026

Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
Published on: May 10, 2021
Infective endocarditis superimposed on a massively calcified severely stenotic congenitally bicuspid aortic valve
Syed Sarmast1, Jeffrey M Schussler1, Jong M Ko1
1Division of Cardiology, Department of Internal Medicine, Baylor University Medical Center at Dallas and the Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.
Abstract:
We describe a 55-year-old man who presented with a stroke resulting from active infective endocarditis (IE) involving a heavily calcified bicuspid aortic valve. The case highlights the infrequency of IE involving a heavily calcified valve, the inability of the infection to penetrate the calcific deposits, and the ability of the infection to spread to the adjacent soft tissues, leading to ring abscess and its multiple complications.
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