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Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients

Adeseye A Akintunde1, Philip B Adebayo, Ademola A Aremu

  • 1Akintunde A.A., P.O. Box 3238, Osogbo, Nigeria, iakintunde2@yahoo.com.

Croatian Medical Journal
|January 3, 2014
PubMed

Insights

Hypertension is linked to right ventricular diastolic dysfunction (DD) and carotid atherosclerosis in Nigerian patients. Increased carotid intima media thickness may indicate DD in hypertensive individuals.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Hypertension Research

Background:

  • Hypertension is a significant risk factor for cardiovascular complications, including cardiac and vascular abnormalities.
  • Right ventricular diastolic dysfunction (DD) and carotid atherosclerosis are common in hypertensive patients.
  • Understanding the association between these conditions is crucial for risk stratification and management.

Purpose of the Study:

  • To investigate the relationship between carotid atherosclerosis and right ventricular diastolic dysfunction (DD) in treated hypertensive Nigerian patients.
  • To explore the potential of carotid intima media thickness as a marker for DD in this population.

Main Methods:

  • A single-center, cross-sectional study involving 122 treated hypertensive Nigerian patients.
  • Echocardiographic parameters, including trans-tricuspid Doppler flow, were used to assess diastolic function.
  • Carotid intima media thickness was measured to evaluate atherosclerosis.

Main Results:

  • Patients with right ventricular DD were older and had significantly higher mean and maximum carotid intima media thickness compared to those without DD.
  • Higher systolic blood pressure and interventricular septal thickness were observed in patients with DD.
  • Tricuspid annular pulmonary systolic excursion was significantly lower in patients with right ventricular DD.

Conclusions:

  • Right ventricular DD is significantly associated with increased carotid atherosclerosis in hypertensive patients.
  • Carotid intima media thickness measurements may serve as a surrogate marker for right ventricular DD in hypertensive individuals.
  • This finding highlights the importance of assessing vascular health in hypertensive patients with potential cardiac dysfunction.
Abstract

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