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Scleredema: report of a case
M Tanaka1, S Kobayashi, Y Kumagai
1Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine , 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421 , Japan.
Modern Rheumatology
|January 4, 2014
Summary
Scleredema, a rare skin condition causing thickened skin, was observed in a patient with diabetes mellitus. Controlling blood sugar levels led to significant improvement in the skin lesions.
Area of Science:
- Dermatology
- Endocrinology
- Pathology
Background:
- Scleredema is a rare connective tissue disorder characterized by thickened skin.
- Cutaneous manifestations of scleredema require differentiation from other conditions like scleroderma.
Purpose of the Study:
- To describe a case of scleredema in a patient with diabetes mellitus.
- To highlight the relationship between glycemic control and scleredema improvement.
Main Methods:
- Clinical observation of a patient presenting with thickened skin.
- Histopathological examination of a skin biopsy.
- Monitoring of skin lesion response to diabetes mellitus treatment.
Main Results:
- A patient presented with thickened skin on the neck, shoulders, and back.
- Skin biopsy confirmed thickened dermis with abundant collagen bundles.
- Skin lesions resolved within one month after controlling diabetes mellitus with oral hypoglycemics.
Conclusions:
- Scleredema can be associated with diabetes mellitus.
- Effective management of underlying diabetes mellitus can lead to amelioration of scleredema.
- Distinguishing scleredema from scleroderma is clinically important.
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